Citrate transporter family protein

WebMar 11, 2016 · Multidrug and toxic compound extrusion (MATE) family is the most recent categorized multidrug efflux transporter family, which is a secondary transporter family that couples the translocation of substrates with an electrochemical gradient of cations (such as H + or Na + ions) across the membrane [1, 2].The X-ray structure of the MATE … WebFeb 17, 2024 · Liver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity drugs.

Plant transporters: roles in stress responses and effects on

WebAluminum-activated malate transporter 1. Gene. ALMT1. Status. UniProtKB reviewed (Swiss-Prot) ... Al tolerance QTL also found on chromosome 1. Acts in parallel but independently of MATE, an aluminum-activated root citrate transporter. ... Protein family/group databases. TCDB. 2.A.85.2.3 the aromatic acid exporter (arae) family; … WebAn insertion in the rice citrate efflux transporter gene OsFRDL4 increased its promoter activity and improved its expression, thereby enhancing Al tolerance ... The PHT family protein PHT5 in the vacuolar membrane regulates cytoplasmic Pi homeostasis to enhance plant growth under Pi deficiency (Lin et al. 2024; ... fit n fast knoxville tn https://airtech-ae.com

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WebMar 1, 2024 · The Mitochondrial Carrier Family. With 53 members, the mitochondrial carrier family (solute carrier family 25, SLC25) is the largest solute transporter family in humans. They transport solutes across the impermeable inner membrane of mitochondria for important cellular processes, such as oxidative phosphorylation of fats and sugars, … WebJun 14, 2024 · Introduction. L-lactate is an important metabolite in health and disease 1. Its stereoselective transport across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the ... WebSLC13A5. Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. [5] It is the mammalian homolog of the fly Indy gene . caniche avec frange

Towards sustainable use of acidic soils: Deciphering

Category:Structure and inhibition mechanism of the human citrate transporter

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Citrate transporter family protein

The Mitochondrial Citrate Carrier SLC25A1/CIC and the ... - PubMed

WebCitrate transporter family protein Imported. Gene names. Ordered locus names. PFL_2499 Imported. Organism names. Organism. Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) Imported. Taxonomic … WebSep 29, 2012 · The 2-oxoglutarate carrier (OGC) belongs to the mitochondrial carrier protein family whose members are responsible for the exchange of metabolites, cofactors and nucleotides between the cytoplasm and mitochondrial matrix. Initially, OGC was characterized by determining substrate specificity, kinetic parameters of transport, …

Citrate transporter family protein

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WebNational Center for Biotechnology Information WebAbstract. Citrate, an organic trivalent anion, is a major substrate for generation of energy in most cells. It is produced in mitochondria and used either in the Krebs' cycle or released …

WebMay 14, 2024 · The citrate transport activity of the protein was studied in CT reconstituted liposomes. Our results showed high efficiency of CT for [ 14 C] citrate/citrate exchange with K m 0.01 mM at 25°C. WebProtein family/group databases. TCDB. 2.A.29.7.1 the mitochondrial carrier (mc) family; Names & Taxonomy. Protein names ... Citrate carrier 1 publication (CIC 1 publication) …

WebMay 14, 2024 · To study the citrate transport mechanism of CT, the citrate transporter gene was expressed in Escherichia coli, and its product was purified. The citrate … WebNov 14, 2008 · Recently, three studies have reported that some MATE proteins are involved in the transport of citrate, which is required for iron (Fe) translocation or …

WebOct 29, 2024 · Summary. This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and ...

WebSLC25 is the largest solute transporter family in humans. 53 members have been ... (SLC25A1, or citrate transport protein; TC# 2.A.29.7.2) Graves disease carrier protein … fit n fast hallsWebDec 15, 2024 · Iacobazzi et al. (1997) determined that the open reading frame of the human citrate transporter gene encodes a mature protein of 298 amino acids and a … fitney coWebCitrate plays a pivotal role not only in the generation of metabolic energy but also in the synthesis of fatty acids, isoprenoids, and cholesterol in mammalian cells. Plasma levels … can i check a cigar torch on a planeWebLiver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity … fit n fast sydney liverpool streetWebJun 1, 2003 · Protein family/group databases. TCDB. 2.A.47.1.9 the divalent anion:na + symporter (dass) family; Names & Taxonomy. Protein names. ... Sodium-coupled citrate transporter 1 publication. Sodium-dependent citrate transporter; Solute carrier family 13 member 5; Gene names. Name. SLC13A5. Synonyms. NACT. Organism names. … can i check a beach chairWebTricarboxylate transport protein, mitochondrial, also known as tricarboxylate carrier protein and citrate transport protein (CTP), is a protein that in humans is encoded by … can i check a dbs number onlineWebOct 10, 2013 · The SLC13 family in humans and other mammals consists of sodium-coupled transporters for anionic substrates: three transporters for dicarboxylates/citrate and two transporters for sulfate. This review will focus on the di- and tricarboxylate transporters: NaDC1 (SLC13A2), NaDC3 (SLC13A3), and NaCT (SLC13A5). The substrates of these … fit n fab box