WebThis maturation process was perturbed by specific inactivation of either NF-κB or IFN regulatory factor 1 (IRF1) in cDC1s, resulting in impaired expression of IFN-γ–responsive genes and consequently a failure to efficiently recruit and activate antitumoral CD8 + T cells. WebNov 2, 2024 · The high expression of IRF1 during hepatic IR exhibited increased liver damage and was associated with activation of autophagy …
Anti-phospho-c-Abl(Tyr272)抗体 - 上海康朗生物科技有限公司
WebJan 15, 2024 · By searching the X. tropicalis genome, a putative IRF1 gene named Xt-IRF1 was identified on chromosome 3 (NCBI Reference Sequence: NC_030679.2). To test whether predicted IRF1 gene is expressed in vivo at transcription level, the ORF sequence of Xt-IRF1 gene was cloned from frog, with the following accession number in GenBank: MT586025. … WebAug 1, 2024 · IRF1 is an early-target gene downstream of IFNγ signaling and modulates IFNγ-mediated gene induction ( 19 ). IRF1 also regulates constitutive and inducible … small trees for courtyards nz
Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 ... - PNAS
WebJun 18, 2024 · Abstract. Interferon regulatory factor 1 (IRF1) regulates diverse biological functions, including modulation of cellular responses involved in tumorigenesis. Genetic mutations and altered IRF1 function are associated with several cancers. Although the function of IRF1 in the immunobiology of cancer is emerging, IRF1-specific mechanisms ... WebAlkaline phosphatase (ALP) is an enzyme that’s found throughout your body. ALP blood tests measure the level of ALP in your blood that comes from your liver and bones, and it’s … WebPhospho-IRF-7 (Ser471/472) Antibody detects transfected levels of IRF-7 when phosphorylated at Ser471 and 472. Species Reactivity: Human Source / Purification … small trees for containers